Cognitive impulsivity in Parkinson's disease patients: Assessment and pathophysiology
Identifieur interne : 000B32 ( Main/Exploration ); précédent : 000B31; suivant : 000B33Cognitive impulsivity in Parkinson's disease patients: Assessment and pathophysiology
Auteurs : Gabriel Robert [France] ; Dominique Drapier [France] ; Marc Verin [France] ; Bruno Millet [France] ; Jean-Philippe Azulay [France] ; Olivier Blin [France]Source :
- Movement Disorders [ 0885-3185 ] ; 2009-12-15.
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Abstract
Impulsivity may be induced by therapeutic interventions (dopamine replacement therapies and sub‐thalamic nucleus (STN) stimulation) in patients with Parkinson's disease (PD). The present review has two goals. First, to describe the most frequently encountered facets of cognitive impulsivity and to stress the links between cognitive impulsivity and aspects such as reward‐related decision making, risk‐taking, and time‐processing in healthy population. The most widely used related cognitive impulsivity paradigms are presented. Second, to review the results of studies on cognitive impulsivity in healthy volunteers and in patients with PD, the latter support the applicability and clinical relevance of this construct in PD population. Data show that PD treatments may favor impulsivity via different mechanisms. Suggestions on the roles of dopamine and STN in the pathophysiology of cognitive impulsivity are proposed. © 2009 Movement Disorder Society
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DOI: 10.1002/mds.22836
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Suggestions on the roles of dopamine and STN in the pathophysiology of cognitive impulsivity are proposed. © 2009 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>France</li></country><settlement><li>Marseille</li><li>Rennes</li></settlement></list><tree><country name="France"><noRegion><name sortKey="Robert, Gabriel" sort="Robert, Gabriel" uniqKey="Robert G" first="Gabriel" last="Robert">Gabriel Robert</name></noRegion><name sortKey="Azulay, Jean Hilippe" sort="Azulay, Jean Hilippe" uniqKey="Azulay J" first="Jean-Philippe" last="Azulay">Jean-Philippe Azulay</name><name sortKey="Blin, Olivier" sort="Blin, Olivier" uniqKey="Blin O" first="Olivier" last="Blin">Olivier Blin</name><name sortKey="Drapier, Dominique" sort="Drapier, Dominique" uniqKey="Drapier D" first="Dominique" last="Drapier">Dominique Drapier</name><name sortKey="Drapier, Dominique" sort="Drapier, Dominique" uniqKey="Drapier D" first="Dominique" last="Drapier">Dominique Drapier</name><name sortKey="Millet, Bruno" sort="Millet, Bruno" uniqKey="Millet B" first="Bruno" last="Millet">Bruno Millet</name><name sortKey="Millet, Bruno" sort="Millet, Bruno" uniqKey="Millet B" first="Bruno" last="Millet">Bruno Millet</name><name sortKey="Robert, Gabriel" sort="Robert, Gabriel" uniqKey="Robert G" first="Gabriel" last="Robert">Gabriel Robert</name><name sortKey="Robert, Gabriel" sort="Robert, Gabriel" uniqKey="Robert G" first="Gabriel" last="Robert">Gabriel Robert</name><name sortKey="Verin, Marc" sort="Verin, Marc" uniqKey="Verin M" first="Marc" last="Verin">Marc Verin</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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